EC Number |
Inhibitors |
Structure |
---|
1.14.11.6 | 5-Ethynyluracil |
binds covalently to a phenylalanine residue of the enzyme |
|
1.14.11.6 | 5-Ethynyluracil |
mechanism-based inactivator |
|
1.14.11.6 | 5,6-Dihydrothymine |
73% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 6-Azathymine |
94% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 5-Aminouracil |
100% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 5-Hydroxyuracil |
92% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 6-Methyluracil |
18% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 1-methylthymine |
73% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 1-Methyluracil |
80% inhibition at 5 mM with thymine as substrate |
|
1.14.11.6 | 1-ethylthymine |
70% inhibition at 5 mM with thymine as substrate |
|