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Results 1 - 4 of 4
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EC Number Activating Compound Commentary Reference
Show all pathways known for 6.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.11Intact SH-groups required for activity 85
Show all pathways known for 6.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.11Pex21p the enzyme interacts with the peroxisome biogenesis-related factor Pex21p, the C-terminally appended domain of yeast seryl-tRNA synthetase does not participate in substrate binding, but instead is required for association with Pex21p, Pex21p does not directly bind tRNA, and nor does it possess a tRNA-binding motif, but it instead participates in the formation of a specific ternary complex with seryl-tRNA synthetase and tRNASer, strengthening the interaction of seryl-tRNA synthetase with its cognate tRNASer, overview 673593
Show all pathways known for 6.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.11tRNASer binding to the enzyme enhances the discrimination of the amino acid substrate and the activity, and diminishes the rate of misactivation of threonine, all due to a conformational chage in the enzymes active site 651138
Show all pathways known for 6.1.1.11Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.11tRNASer promotes the binding of the other substrates, probably due to a conformational change in motif 2 region 650314
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