EC Number |
Activating Compound |
Reference |
---|
3.1.1.79 | 2-mercaptoethanol |
at 1% |
750161 |
3.1.1.79 | betaine |
it enhances the enzyme activity 2fold at 50°C and 3 M, and 1.5fold at 45°C and 1-3 M, while it reduces the enzyme activity at 35-40°C, by 20% at 40°C and 3 M, about 5% at 1 M, overview |
729483 |
3.1.1.79 | cyclic AMP-dependent protein kinase |
phosphorylation, 40% activation of triolein hydrolyzing activity |
646086 |
3.1.1.79 | DMSO |
increase in enzyme activity (130%) is observed at 25% v/v DMSO although at a higher concentration (50%), DMSO decreases enzyme activity to 72% |
750161 |
3.1.1.79 | DTT |
at 1% |
750161 |
3.1.1.79 | HSL inhibitor |
reduced activity in macrophage foam cells due to increased activity of an inhibitor protein |
654152 |
3.1.1.79 | L-methionine |
L-methionine enhances the enzyme activity in absence of tumor necrosis factor-alpha, but inhibits it in presence of TNF-alpha |
714794 |
3.1.1.79 | more |
activity in incubated soleus muscle increases in response to adrenaline |
654475 |
3.1.1.79 | more |
proline does not activate and thermally stabilize the enzyme at 35-50°C and concentrations of 1-3 M, but inhibits the enzyme activity |
729483 |
3.1.1.79 | more |
stearate and palmitate, saturated fatty acids but not unsaturated fatty acids (oleate and linoleate) induce up-regulation of HSL mRNA in a time- and concentration-dependent manner in bMEC. Oleate and linoleate induce no up-regulation of HSL mRNA |
690757 |