EC Number |
Activating Compound |
Reference |
---|
3.1.1.47 | corticoids |
regulatory function on the enzyme form from HL-60 cells |
650326 |
3.1.1.47 | corticoids |
regulatory function on the enzyme form from plasma |
650326 |
3.1.1.47 | deoxycholate |
activation |
80945 |
3.1.1.47 | dithiothreitol |
1.3fold increase in activity, isozyme II from cerebrospinal fluid |
649522 |
3.1.1.47 | dithiothreitol |
slightly acivating |
653094 |
3.1.1.47 | dyslipidemia |
induces an increase in total plasma enzyme activity and alters the enzyme distribution between proatherogenic apoB- and antiatherogenic apo L-containing lipoproteins by increasing the enzyme activity associated with apoB-containing lipoproteins, atorvastin and fenofibrate can restore the normal level by reduction of LDL amount |
649802 |
3.1.1.47 | GM-CSF |
regulatory function on the enzyme form from monocyte-derived macrophages |
650326 |
3.1.1.47 | interleukin-beta |
regulatory function on the enzyme form from plasma, liver and spleen |
650326 |
3.1.1.47 | lipopolysaccharides |
induce plasma enzyme expression in several tissues, overview, induction is 50% inhibited by administration of antagonists BN 50739 and WEB 2170 |
652009 |
3.1.1.47 | lipopolysaccharides |
regulatory function on the enzyme form from plasma |
650326 |