EC Number   |
Activating Compound |
Reference |
|---|
    2.7.2.3 | (NH4)2SO4 |
inhibition at high concentration, acceleration of activity at low concentrations |
642252 |
| 2.7.2.3 | 1,3-diphosphoglycerate |
substrate activation |
642275 |
| 2.7.2.3 | acetate |
as Na or K salt continues to activate at concentrations above 200 mM |
661242 |
| 2.7.2.3 | ATP4- |
binds to the free enzyme as an inhibitor, when binding to the enzyme-MgATP2-(3-phospho-D-glycerate)complex, ATP4- acts as an activator |
642245 |
| 2.7.2.3 | ATP4- |
inhibition at high concentration, acceleration of activity at low concentrations |
642245, 642252 |
| 2.7.2.3 | Calmodulin |
a significant increase (1.8 times) in enzyme activity is observed in the co-presence of calmodulin (0.001 mM) and CaCl2 (0.01 mM). The enzyme activity remains unaltered in the presence of either calcium or calmodulin alone |
760650 |
| 2.7.2.3 | Calmodulin |
the enzyme is activated up to 85% in the presence of 0.001 mM calmodulin |
760650 |
| 2.7.2.3 | more |
enzyme is regulated by multivalent anions, overview |
642289 |
| 2.7.2.3 | more |
hypoxic treatment induces the protein expression of PGK 3fold, induction of HIF-1alpha by addition of 0.5 mM dimethyloxallyl glycine increases PGK expression under normoxic conditions |
682025 |
| 2.7.2.3 | more |
in bloodstream forms, after XRNA depletion, abundance of PGKB mRNA increases to about one-third of the PGKC mRNA abundance, with a corresponding decrease in the apparent degradation rate. The degradation of PGKC mRNA is not affected. In procyclic forms, PGKB mRNA is unaffected by XRNA depletion, PGKC mRNA is undetectable, but after XRNA depletion, PGKC mRNA is detectable |
681818 |
