Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme is regulated by multivalent anions, overview | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,5-Bisphosphonopentane | competitive | Sus scrofa | |
2,3-diphosphoglycerate | - |
Sus scrofa | |
2-Phosphoglycolate | competitive | Sus scrofa | |
adenosine | - |
Sus scrofa | |
Glycerol 2-phosphate | competitive | Sus scrofa | |
glycerol 3-phosphate | competitive | Sus scrofa | |
additional information | double-inhibition studies, kinetics, modeling of inhibitor binding, e.g. phosphate; enzyme is regulated by multivalent anions, overview | Sus scrofa | |
phosphate | - |
Sus scrofa | |
SO42- | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 3-phospho-D-glycerate | - |
Sus scrofa | ADP + 1,3-diphosphoglycerate | - |
r | |
additional information | enzyme is regulated by multivalent anions | Sus scrofa | ? | - |
? | |
additional information | 2-domain hinge-binding enzyme | Sus scrofa | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Sus scrofa | |
ATP | required as phosphate donor | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.35 | - |
2,3-diphosphoglycerate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
0.7 | - |
glycerol 3-phosphate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
4 | - |
2-Phosphoglycolate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
8.3 | - |
phosphate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
9.6 | - |
Glycerol 2-phosphate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
14 | - |
sulfate | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa | |
26 | - |
1,5-Bisphosphonopentane | pH 7.5, 20°C, versus 3-phospho-D-glycerate | Sus scrofa |