EC Number   |
Activating Compound |
Reference |
|---|
   2.7.1.127 | 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane |
5-HT2 agonist DOI, 3fold activation |
640746 |
| 2.7.1.127 | 12-O-tetradecanoyl phorbol 13-acetate |
stimulating in presence of cAMP |
661446 |
| 2.7.1.127 | 12-O-tetradecanoylphorbol-13-acetate |
2fold activation, isoform B |
640758 |
| 2.7.1.127 | 1D-myo-inositol 1,3,4,5-tetrakisphosphate |
recombinant, catalytically active fragment of isoform C, allosteric product activation in the absence of Ca2+/calmodulin, which per se activates enzyme and abolishes the allosteric effect |
640761 |
| 2.7.1.127 | 5-HT |
2-3fold activation |
640746 |
| 2.7.1.127 | Ca2+/calmodulin |
for enzyme activation, Ca2+/calmodulin, 2.15 microg/ml calmodulin and 10-20 microM free CaCl2 is added to the assay mixture |
699006 |
| 2.7.1.127 | Ca2+/CaM-dependent kinase II |
i.e. CaMKII, activates the enzyme by phosphorylation at a Thr residue |
661446 |
| 2.7.1.127 | Ca2+/CaM-dependent kinase II |
i.e. CaMKII, activates the enzyme by phosphorylation of Thr311 |
661446 |
| 2.7.1.127 | Ca2+/CaM-dependent kinase II |
i.e. CaMKII, activates the enzyme by phosphorylation of threonine residue |
661446 |
| 2.7.1.127 | Calmodulin |
2-3fold activation of isozyme IP33K-A and 7-8fold of isozyme IP33K-B, in a Ca2+-dependent manner, the binding site contains amphiphilic alpha-helices with cluster of positively charged and hydrophobic amino acids |
661446 |
