EC Number |
Activating Compound |
Reference |
---|
2.3.1.57 | more |
amino acid deprivation upregulates enzyme expression level of 2 different mRNA forms |
661893 |
2.3.1.57 | more |
certain stresses induce enzyme by a spermidine-dependent post-transcriptional mechanism, e.g. heat shock, diethyldithiocarbamate and high levels of endogenous spermidine, alpha-difluoromethylornithine inhibits stress induction |
487265 |
2.3.1.57 | more |
enzyme is highly inducible by polyamine analogues such as N1,N12-bis(ethyl)spermine and N1,N11-bis(ethyl)norspermine, they prevent enzyme degradation via the Ub/proteasome pathway, mechanism |
487268 |
2.3.1.57 | more |
enzyme is induced by growth hormone, thioacetamide, dialkylnitrosamines, folic acid and spermidine |
487258 |
2.3.1.57 | more |
enzyme is induced by isopropyl beta-D-thiogalactopyranoside |
487263, 487264 |
2.3.1.57 | more |
enzyme is induced by methylglyoxal bis(guanylhydrazone), potentiated by tetronasin or felodipine, tetronasin is also an active inducer, induction is related to the concentration of intracellular free calcium |
487262 |
2.3.1.57 | more |
enzyme is induced by treatment with hepatotoxins, e.g. carbon tetrachloride |
487257, 487258 |
2.3.1.57 | more |
indomethacin and excess polyamines induce SSAT activity |
487270 |
2.3.1.57 | more |
kainate-induced seizures increase SSAT activity |
701622 |
2.3.1.57 | more |
N1,N11-diethylnorspermine induces SSAT activity by post-mRNA regulation |
487267 |