EC Number |
Activating Compound |
Reference |
---|
1.8.1.9 | carbon tetrachloride |
causes marked increases in hepatic TrxR1 activity |
690139 |
1.8.1.9 | cysteine |
- |
394937 |
1.8.1.9 | cysteine |
1 pair of redox active cysteines at the N-terminal active center and 1 pair of selenenylsulfide at the C-terminus, crucial for the reduction of thioredoxin |
394938 |
1.8.1.9 | cysteine |
1 redox-active disulfide per subunit |
394933 |
1.8.1.9 | cysteine |
2 pairs of cysteine residues, C32, C35 and C135, C138 |
394946 |
1.8.1.9 | cysteine |
at the active center, C88 and C93 |
394943 |
1.8.1.9 | cysteine |
C-terminal redox active disulfide |
394947, 394949 |
1.8.1.9 | cysteine |
C-terminal redox active selenocysteine motif |
394952 |
1.8.1.9 | cysteine |
part of the active site |
394916, 394918, 394921, 394925, 394932, 394939, 394941, 394942, 394947 |
1.8.1.9 | EDTA |
4% activity remaining without |
394952 |