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BTO (BRENDA Tissue Ontology)

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Change ontology: Version 2021-10-23

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Tissue

Details for foreign-body giant cell

BTO (BRENDA Tissue Ontology) ID

BTO:0003107

Definition

Syncytium formed by the fusion of macrophages in response to an indigestible particle too large to be phagocytosed for example talc, silica or asbestos fibres. Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells, but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm

Synonyms

1. foreign body giant cell

References

1. Medical Dictionary Online: http://www.online-medical-dictionary.org//
2. Online Medical Dictionary: http://cancerweb.ncl.ac.uk/

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is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

tissues, cell types and enzyme sources

animal

whole body is a

blood

foreign-body giant cell

mononuclear cell is a

mononuclear phagocyte is a

monocyte

macrophage

foreign-body giant cell

phagocyte

mononuclear phagocyte is a

monocyte

macrophage

foreign-body giant cell

marrow cell is a

mononuclear phagocyte is a

monocyte

macrophage

foreign-body giant cell

blast cell

hematopoietic stem cell

myeloid progenitor cell

marrow cell

mononuclear phagocyte is a

monocyte

macrophage

foreign-body giant cell

pluripotent stem cell

adult stem cell is a

hematopoietic stem cell is a

myeloid progenitor cell

marrow cell

mononuclear phagocyte is a

monocyte

macrophage

foreign-body giant cell

immune system

macrophage

foreign-body giant cell

Tree view

tissues, cell types and enzyme sources

tissues, cell types and enzyme sources is a

animal

whole body is a

body wall

cardiovascular system part of

connective tissue part of

embryonic structure is a

gland

head

hematopoietic system part of

blood

arterial blood is a

blast cell part of

hematopoietic stem cell derives from

immune stem cell derives from

leukemic stem cell derives from

lymphoid progenitor cell derives from

myeloid progenitor cell derives from

marrow cell derives from

erythroblast is a

megakaryocyte is a

mononuclear phagocyte is a

monocyte

macrophage derives from

alveolar macrophage is a

bone marrow-derived macrophage is a

epitheloid cell derives from

foreign-body giant cell derives from

histiocyte is a

interstitial macrophage is a

Langerhans cell is a

Langhans giant cell is a

M1 macrophage is a

M2 macrophage is a

macrophage cell line derives from

ANA-1 cell is a

BMA cell

BMC-2 cell is a

HD-11 cell is a

J-774 cell is a

J-774.1 cell is a

J-774A.1 cell is a

J774.2 cell is a

RAW-264.7 cell is a

peritoneal macrophage is a

splenocyte is a

premonocyte is a

myeloid cell line derives from

normoblast is a

polymorphonuclear leukocyte is a

promyelocyte is a

blood clot derives from

blood plasma part of

granuloma cell

hematopoietic cell part of

peripheral blood part of

venous blood is a

hemolymph

hemolymph vessel part of

lymph

lymph vessel part of

lymphoid tissue part of

reticuloendothelial system part of

serum

immune system part of

integument part of

limb

muscular system part of

nervous system part of

pacemaker cell part of

pluripotent stem cell part of

primary cell part of

respiratory system part of

sense organ part of

skeletal system part of

soft body part part of

trunk

urogenital system part of

viscus

fungus

organism form is a

other source is a

plant