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Gene ontology
Version 2014-12-22
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Details for titin-telethonin complex
Gene ontology ID
GO:1990733
Definition
A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils
Comment
An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).
Synonyms
1. Titin-Tcap complex
References
1. GOC: ame
2. PMID 16407954
3. IntAct: EBI-10711453
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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