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Gene ontology
Version 2014-12-22
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Details for peptidyl-proline 4-dioxygenase activity
Gene ontology ID
GO:0031545
Definition
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2
Synonyms
1. HIF-type prolyl 4-hydroxylase
2. prolyl 4-hydroxylase
References
1. GOC: mah
2. Reactome: R-HSA-1234165 "Nuclear PHD1,3 hydroxylates proline residues on HIF3A"
3. Reactome: R-HSA-1234166 "Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A)"
4. Reactome: R-HSA-1234173 "Cytosolic PHD2,3 hydroxylates proline residues on HIF3A"
5. Reactome: R-HSA-1234177 "Cytosolic PHD2,3 hydroxylates proline residues on HIF1A"
6. Reactome: R-HSA-1234179 "Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A)"
7. Reactome: R-HSA-1234181 "Nuclear PHD1,3 hydroxylates proline residues on HIF1A"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular macromolecule metabolic process is a
cellular protein metabolic process is a
cellular protein modification process is a
peptidyl-amino acid modification is a
peptidyl-proline modification is a
peptidyl-proline hydroxylation is a
peptidyl-proline dioxygenase activity part of
peptidyl-proline 4-dioxygenase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular protein metabolic process is a
CAAX-box protein maturation is a
cellular protein modification process is a
co-translational protein modification is a
enzyme active site formation is a
ISG15-protein conjugation is a
metal incorporation into metallo-molybdopterin complex is a
metal incorporation into metallo-oxygen cluster is a
N-terminal protein amino acid modification is a
nucleic acid-protein covalent cross-linking is a
peptide cross-linking is a
peptidyl-amino acid modification is a
peptidyl-alanine modification is a
peptidyl-arginine modification is a
peptidyl-asparagine modification is a
peptidyl-aspartic acid modification is a
peptidyl-cysteine modification is a
peptidyl-glutamic acid modification is a
peptidyl-glutamine modification is a
peptidyl-glycine modification is a
peptidyl-histidine modification is a
peptidyl-isoleucine modification is a
peptidyl-L-amino acid racemization is a
peptidyl-leucine modification is a
peptidyl-lysine modification is a
peptidyl-methionine modification is a
peptidyl-phenylalanine modification is a
peptidyl-proline modification is a
C-terminal peptidyl-proline amidation is a
peptidyl-proline hydroxylation is a
peptidyl-proline di-hydroxylation is a
peptidyl-proline dioxygenase activity part of
peptidyl-proline 3-dioxygenase activity is a
peptidyl-proline 4-dioxygenase activity is a
procollagen-proline dioxygenase activity is a
peptidyl-proline hydroxylation to 3-hydroxy-L-proline is a
peptidyl-proline hydroxylation to 4-hydroxy-L-proline is a
protein peptidyl-prolyl isomerization is a
peptidyl-selenocysteine modification is a
peptidyl-serine modification is a
peptidyl-threonine modification is a
peptidyl-tryptophan modification is a
peptidyl-tyrosine modification is a
peptidyl-valine modification is a
post-translational protein modification is a
protein acylation is a
protein ADP-ribosylation is a
protein alkylation is a
protein amidation is a
protein biotinylation is a
protein carbamoylation is a
protein carboxylation is a
protein de-ADP-ribosylation is a
protein deacylation is a
protein dealkylation is a
protein deamination is a
protein deglutathionylation is a
protein deglycation is a
protein deglycosylation is a
protein dehydration is a
protein delipidation is a
protein denucleotidylation is a
protein dephosphorylation is a
protein desulfurization is a
protein esterification is a
protein flavinylation is a
protein glucuronidation is a
protein glutathionylation is a
protein halogenation is a
protein hydroxylation is a
protein initiator methionine removal is a
protein modification by small protein conjugation or removal is a
protein nitrosylation is a
protein nucleotidylation is a
protein oxidation is a
protein phosphopantetheinylation is a
protein phosphorylation is a
protein polyamination is a
protein prenylation is a
protein sialylation is a
protein sulfation is a
protein sulfhydration is a
protein tyrosinylation is a
protein-chromophore linkage is a
protein-cofactor linkage is a
protein-tetrapyrrole linkage is a
ferredoxin metabolic process is a
mitochondrial protein processing is a
Notch receptor processing is a
prosthetic group metabolic process part of
protein repair is a
rhodopsin metabolic process is a
signal peptide processing is a
vacuolar protein processing is a
glycoprotein metabolic process is a
hemoglobin metabolic process is a
macromolecule methylation is a
poly-gamma-glutamate metabolic process is a
receptor metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a