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Gene ontology
Version 2014-12-22
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Details for 1-phosphatidylinositol-3-phosphate 5-kinase activity
2.7.1.150
Gene ontology ID
GO:0000285
Definition
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+)
Synonyms
1. ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity
2. phosphatidylinositol 3-phosphate 5-kinase activity
3. phosphatidylinositol-3-phosphate 5-kinase activity
4. type III PIP kinase activity
References
1. EC 2.7.1.150
2. RHEA: 13609
3. KEGG REACTION: R05802
4. MetaCyc 2.7.1.150-RXN
5. Reactome: R-HSA-1675910 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane"
6. Reactome: R-HSA-1675921 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane"
7. Reactome: R-HSA-1676134 "PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane"
8. Reactome: R-HSA-1676168 "PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane"
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