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Gene ontology
Version 2014-12-22
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Details for mRNA splicing, via spliceosome
Gene ontology ID
GO:0000398
Definition
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced
Comment
Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
Synonyms
1. mRNA splicing
2. nuclear mRNA splicing via U12-type spliceosome
3. nuclear mRNA splicing via U2-type spliceosome
4. nuclear mRNA splicing, via spliceosome
5. pre-mRNA splicing
6. splicing AT-AC intron
7. splicing GT-AG intron
References
1. GOC: krc
2. ISBN 0198506732
3. ISBN 0879695897
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