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Literature summary for 7.6.2.3 extracted from

  • Zhang, Y.; Callaway, E.
    High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate (2002), Biochem. J., 364, 301-307 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.6.2.3

Inhibitors

Inhibitors Comment Organism Structure
cyclosporin
-
 Homo sapiens
glibenclamide
-
 Homo sapiens
MK571
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + sulforaphane-S-glutathione[side 1] Homo sapiens
-
 ADP + phosphate + sulforaphane-S-glutathione[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8HXQ5
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HL60/ADR cell
-
 Homo sapiens
-
HL60/S cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
myeloma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + sulforaphane-S-glutathione[side 1]
-
 Homo sapiens ADP + phosphate + sulforaphane-S-glutathione[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
MRP-1
-
 Homo sapiens
multidrug resistance associated protein-1
-
 Homo sapiens
P-glycoprotein-1
-
 Homo sapiens
PGP-1
-
 Homo sapiens