Literature summary for 7.6.2.2 extracted from

Hipfner, D.R.; Mao, Q.; Qi, W.; Leslie, E.M.; Gao, M.; Deeley, R.G.; Cole, S.P.C.
Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP (1999), J. Biol. Chem., 274, 15420-15426.

Search for more literature for 7.6.2.2

Inhibitors

Inhibitors	Comment	Organism	Structure
monoclonal antibiodies	monoclonal antibodies QCRL-2, QCRL-3, and QCRL-4 recognize distinct, non-overlapping epitopes of the enzyme MRP. The ability to inhibit MRP-dependent transport results from direct interactions with the nucleotide-binding domains of the protein that do not prevent the binding of ATP	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	transmembrane protein	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
H69AR cell	-	Homo sapiens	-
HEK-293 cell	-	Homo sapiens	-
HL-60 cell	-	Homo sapiens	-

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Release 2023.1 (January 2023)