Cloned (Comment) | Organism |
---|---|
LdMT is cloned by rescuing the resistance phenotype of the M-40 R cell line overexpression in Leishmania tarentolae | Leishmania donovani |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | - |
Leishmania donovani | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Leishmania donovani | the enzyme is directly involved in miltefosine uptake in eukaryotic cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania donovani | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is directly involved in miltefosine uptake in eukaryotic cells | Leishmania donovani | ? | - |
? | |
additional information | the enzyme is able to promote the translocalisation of aminophospholipids and glycerophosphocholine molecules such as NBD-phosphatidylcholine and edelfosine and non glycerol based alkylphosphocholine miltefosin | Leishmania donovani | ? | - |
? |