Literature summary for 7.5.2.1 extracted from

Bajaj, R.; Park, M.I.; Stauffacher, C.V.; Davidson, A.L.
Conformational dynamics in the binding-protein-independent mutant of the Escherichia coli maltose transporter, MalG511, and its interaction with maltose binding protein (2018), Biochemistry, 57, 3003-3015 .

Search for more literature for 7.5.2.1

Activating Compound

Activating Compound	Comment	Organism	Structure
maltose binding protein	low levels of maltose binding protein stimulate enzyme activity	Escherichia coli

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli AD126 cells	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
L135F/I154S	the binding-protein-independent mutant of Escherichia coli maltose transporter MalFGK2 retains specificity for maltose and shows a high basal ATPase activity in the absence of maltose binding protein	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
maltose binding protein	inhibitory above 0.05 mM	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + maltose-[maltose-binding protein][side 1]	Escherichia coli	-	ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + maltose-[maltose-binding protein][side 1]	-	Escherichia coli	ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]	-	?

Synonyms

Synonyms	Comment	Organism
MalFGK2	-	Escherichia coli
MalG511	the binding-protein-independent mutant L135F/I154S of Escherichia coli maltose transporter MalFGK2 retains specificity for maltose and shows a high basal ATPase activity in the absence of maltose binding protein	Escherichia coli
maltose transporter	-	Escherichia coli

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Release 2023.1 (January 2023)