Literature summary for 7.4.2.1 extracted from

Peter, G.J.; Duering, L.; Ahmed, A.
Carbon catabolite repression regulates amino acid permeases in Saccharomyces cerevisiae via the TOR signaling pathway (2006), J. Biol. Chem., 281, 5546-5552.

Search for more literature for 7.4.2.1

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	uptake of leucine 10fold and of arginine 25fold greater in wild-type yeast grown in galactose medium compared with those grown in glucose medium, increase in amino acid transport is due to carbon metabolite repression	Saccharomyces cerevisiae

Protein Variants

Protein Variants	Comment	Organism
additional information	deletion of gap1delta and agp1delta from the wild-type strain does not alter carbon catabolite repression induced increase in L-leucine uptake, deletion of further amino acid permeases reduces the increase in L-leucine uptake 36% in gnp1delta, 62% in bap2delta and 83% in deltabap2-tat1, deletion of TOR1, which regulates cellular response to changes in nitrogen availibility, from the wild-type abolishes the carbon catabolite repression-induced amino acid uptake	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	strains S288C variant M3750, strain BY4741, strain EY0986, strain Bio101 and strain INVSc1	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + L-arginine/out	-	Saccharomyces cerevisiae	ADP + phosphate + L-arginine/in	-	?
ATP + H2O + L-leucine/out	-	Saccharomyces cerevisiae	ADP + phosphate + L-leucine/in	-	?

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Release 2023.1 (January 2023)