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Literature summary for 7.2.2.1 extracted from

  • Mitome, N.; Sato, H.; Tomiyama, T.; Shimabukuro, K.; Matsunishi, T.; Hamada, K.; Suzuki, T.
    Identification of aqueous access residues of the sodium half channel in transmembrane helix 5 of the Fo-alpha subunit of Propionigenium modestum ATP synthase (2017), Biophys. Physicobiol., 14, 41-47 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM103 cells Propionigenium modestum

Protein Variants

Protein Variants Comment Organism
A214C N-ethylmaleimide significantly inhibits ATP synthesis (18%) and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
A218C N-ethylmaleimide significantly inhibits ATP synthesis (19%) and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
E216C the mutant is not inhibited by N-ethylmaleimide Propionigenium modestum
F217C the mutant shows wild type activity also in the presence of N-ethylmaleimide Propionigenium modestum
G215C N-ethylmaleimide significantly inhibits ATP synthesis (42%) and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
I223C N-ethylmaleimide significantly inhibits ATP synthesis (45%) and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
K219C N-ethylmaleimide significantly inhibits ATP synthesis activity (43%) of the enzyme Propionigenium modestum
N222C N-ethylmaleimide significantly inhibits ATP synthesis and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
N230C N-ethylmaleimide significantly inhibits ATP synthesis (38%) and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum
P220C the mutant shows about wild type activity also in the presence of N-ethylmaleimide Propionigenium modestum
T221C N-ethylmaleimide significantly inhibits ATP synthesis and hydrolysis as well as proton pumping activities of the enzyme Propionigenium modestum

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by N-ethylmaleimide Propionigenium modestum

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Propionigenium modestum 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + n Na+[side 1] Propionigenium modestum
-
 ADP + phosphate + n Na+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Propionigenium modestum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + n Na+[side 1]
-
 Propionigenium modestum ADP + phosphate + n Na+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
Na+-transporting FoF1 ATP synthase
-
 Propionigenium modestum