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Information on EC 7.2.2.1 - Na+-transporting two-sector ATPase

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IUBMB Comments
A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis. The enzyme is similar to EC 7.1.2.2 (H+-transporting two-sector ATPase) but pumps Na+ rather than H+. By analogy to EC 7.1.2.2, it is likely that the enzyme pumps 4 sodium ions for every ATP molecule that is hydrolysed. cf. EC 7.2.2.3, P-type Na+ transporter and EC 7.2.2.4, ABC-type Na+ transporter.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
A1AO ATP synthase, ATP phosphohydrolase (Na+-transporting), ATP synthase, F-type ATP synthase, F1FO-ATPase, KPA1, Lipid-binding protein, Na+ pump, Na+ V-ATPase, Na+(Li+, K+)/H+ antiporter, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
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