BRENDA - Enzyme Database
show all sequences of 6.2.1.65

Anaerobic metabolism of 2-hydroxybenzoic acid (salicylic acid) by a denitrifying bacterium

Bonting, C.F.; Fuchs, G.; Arch. Microbiol. 165, 402-408 (1996) View publication on PubMed

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(2-hydroxybenzoyl)adenylate + CoA
Thauera aromatica
-
AMP + 2-hydroxybenzoyl-CoA
-
-
?
ATP + salicylate
Thauera aromatica
-
diphosphate + (2-hydroxybenzoyl)adenylate
-
-
?
ATP + salicylate + CoA
Thauera aromatica
-
AMP + diphosphate + 2-hydroxybenzoyl-CoA
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Thauera aromatica
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Thauera aromatica
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
328
-
overall reaction, pH 7.5, 35°C
Thauera aromatica
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
(2-hydroxybenzoyl)adenylate + CoA
-
755909
Thauera aromatica
AMP + 2-hydroxybenzoyl-CoA
-
-
-
?
ATP + salicylate
-
755909
Thauera aromatica
diphosphate + (2-hydroxybenzoyl)adenylate
-
-
-
?
ATP + salicylate + CoA
-
755909
Thauera aromatica
AMP + diphosphate + 2-hydroxybenzoyl-CoA
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
2-hydroxybenzoate-CoA ligase
-
Thauera aromatica
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(2-hydroxybenzoyl)adenylate + CoA
Thauera aromatica
-
AMP + 2-hydroxybenzoyl-CoA
-
-
?
ATP + salicylate
Thauera aromatica
-
diphosphate + (2-hydroxybenzoyl)adenylate
-
-
?
ATP + salicylate + CoA
Thauera aromatica
-
AMP + diphosphate + 2-hydroxybenzoyl-CoA
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Thauera aromatica
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
328
-
overall reaction, pH 7.5, 35°C
Thauera aromatica
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
(2-hydroxybenzoyl)adenylate + CoA
-
755909
Thauera aromatica
AMP + 2-hydroxybenzoyl-CoA
-
-
-
?
ATP + salicylate
-
755909
Thauera aromatica
diphosphate + (2-hydroxybenzoyl)adenylate
-
-
-
?
ATP + salicylate + CoA
-
755909
Thauera aromatica
AMP + diphosphate + 2-hydroxybenzoyl-CoA
-
-
-
?
Other publictions for EC 6.2.1.65
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Protein Variants
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
kcat/KM [mM/s]
kcat/KM [mM/s] (protein specific)
755838
Ishiyama
Novel pathway of salicylate d ...
Streptomyces sp. WA46
Appl. Environ. Microbiol.
70
1297-1306
2004
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2
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1
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3
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4
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1
1
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755909
Bonting
Anaerobic metabolism of 2-hyd ...
Thauera aromatica
Arch. Microbiol.
165
402-408
1996
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3
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3
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1
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3
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1
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3
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