Literature summary for 6.1.1.3 extracted from

Ahmad, S.; Muthukumar, S.; Kuncha, S.K.; Routh, S.B.; Yerabham, A.S.; Hussain, T.; Kamarthapu, V.; Kruparani, S.P.; Sankaranarayanan, R.
Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme (2015), Nat. Commun., 6, 7552 .

Search for more literature for 6.1.1.3

Organism

Organism	UniProt	Comment	Textmining
Methanocaldococcus jannaschii	Q58597	-	-
Methanocaldococcus jannaschii ATCC 43067	Q58597	-	-
Pyrococcus abyssi	Q9UZ14	-	-
Pyrococcus furiosus	Q8U176	-	-
Pyrococcus furiosus ATCC 43587	Q8U176	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. A unique proofreading module possessing a D-aminoacyl-tRNA deacylase fold does not use side chains for imparting specificity or for catalysis, the two hallmark activities of enzymes	Methanocaldococcus jannaschii	?	-	?
additional information	proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. A unique proofreading module possessing a D-aminoacyl-tRNA deacylase fold does not use side chains for imparting specificity or for catalysis, the two hallmark activities of enzymes	Pyrococcus abyssi	?	-	?
additional information	proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. A unique proofreading module possessing a D-aminoacyl-tRNA deacylase fold does not use side chains for imparting specificity or for catalysis, the two hallmark activities of enzymes	Pyrococcus furiosus	?	-	?
additional information	proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. A unique proofreading module possessing a D-aminoacyl-tRNA deacylase fold does not use side chains for imparting specificity or for catalysis, the two hallmark activities of enzymes	Pyrococcus furiosus ATCC 43587	?	-	?
additional information	proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. A unique proofreading module possessing a D-aminoacyl-tRNA deacylase fold does not use side chains for imparting specificity or for catalysis, the two hallmark activities of enzymes	Methanocaldococcus jannaschii ATCC 43067	?	-	?

Synonyms

Synonyms	Comment	Organism
MJ1197	-	Methanocaldococcus jannaschii
ThrS	-	Methanocaldococcus jannaschii
ThrS	-	Pyrococcus abyssi
ThrS	-	Pyrococcus furiosus

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Release 2023.1 (January 2023)