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Literature summary for 5.6.2.2 extracted from
- Oxygenated chalcones and bischalcones as a new class of inhibitors of DNA topoisomerase II of malarial parasites (2008), Med. Chem. Res., 17, 234-244.
No PubMed abstract available
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium berghei | - |
chloroquine-sensitive and chloroquine-resistant strains | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| supercoiled DNA + ATP + H2O | - |
Plasmodium berghei | catenated DNA networks + ADP + phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| topo II | - |
Plasmodium berghei |
| Topoisomerase II | - |
Plasmodium berghei |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Plasmodium berghei | |
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Release 2023.1 (January 2023)
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