Literature summary for 5.6.2.2 extracted from

Hung, F.; Luo, D.; Sauve, D.M.; Muller, M.T.; Roberge, M.
Characterization of topoisomerase II-DNA interaction and identification of a DNA-binding domain by ultraviolet laser crosslinking (1996), FEBS Lett., 380, 127-132.

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Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	characterization of the interaction of topoisomerase II with DNA and identification of a DNA-binding domain, conserved DNA-binding mechanism	Saccharomyces cerevisiae	?	-	?
network of DNA rings + ATP + H2O	decatenation	Saccharomyces cerevisiae	monomeric DNA circles + ADP + phosphate	-	?
supercoiled DNA + ATP + H2O	catenation	Saccharomyces cerevisiae	catenated DNA networks + ADP + phosphate	-	?
supercoiled DNA + ATP + H2O	relaxation	Saccharomyces cerevisiae	relaxed DNA + ADP + phosphate	-	?

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Release 2023.1 (January 2023)