Literature summary for 5.6.1.6 extracted from

Serohijos, A.W.; Hegedus, T.; Aleksandrov, A.A.; He, L.; Cui, L.; Dokholyan, N.V.; Riordan, J.R.
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function (2008), Proc. Natl. Acad. Sci. USA, 105, 3256-3261.

Crystallization (Commentary)

Crystallization (Comment)	Organism
3D structure constructed by molecular modeling. Residue F508 mediates a tertiary interaction between the surface of nucleotide-binding domain 1 and a cytoplasmic loop in the C-terminal membrane-spanning domain	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)