Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cilium | - |
Mytilus edulis | 5929 | - |
cilium | - |
Spisula solidissima | 5929 | - |
flagellum | of sperms | Mytilus edulis | - |
- |
flagellum | of sperms | Spisula solidissima | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
14000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
14500 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
16500 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
16500 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
17000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
17000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
21000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
78000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
80000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
82000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
82500 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
90000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
94000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
96000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
96000 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
130000 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
430000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
430000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
430000 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
430000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
450000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
450000 | - |
alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
450000 | - |
alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
450000 | - |
alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a dynein associated with a microtubule at position n | Mytilus edulis | - |
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
ATP + H2O + a dynein associated with a microtubule at position n | Spisula solidissima | - |
ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mytilus edulis | - |
blue mussel | - |
Spisula solidissima | - |
surf clam | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | cyclic AMP-dependent phosphorylation takes place on specific light chains in cilia but only on alpha heavy chains in flagella, phosphorylation has no effect on steady-state ATPase activity | Mytilus edulis |
side-chain modification | cyclic AMP-dependent phosphorylation takes place on specific light chains in cilia but only on alpha heavy chains in flagella, phosphorylation has no effect on steady-state ATPase activity | Spisula solidissima |
Purification (Comment) | Organism |
---|---|
high-salt extraction, sucrose gradient | Mytilus edulis |
high-salt extraction, sucrose gradient | Spisula solidissima |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
semen | - |
Mytilus edulis | - |
semen | - |
Spisula solidissima | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.14 | - |
sperm flagellar axonemes | Mytilus edulis |
0.62 | - |
salt extract with detergent | Mytilus edulis |
0.72 | - |
salt extract | Mytilus edulis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a dynein associated with a microtubule at position n | - |
Mytilus edulis | ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? | |
ATP + H2O + a dynein associated with a microtubule at position n | - |
Spisula solidissima | ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? |
Subunits | Comment | Organism |
---|---|---|
oligomer | alpha1,alpha2,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 96000 + 1 * 82000 + 1* 18000 + 1 * 16500 + 1 * 14000, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
oligomer | alpha1,alpha2,IC2,IC3,LC1,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 94000 + 1 * 80000 + 1* 27000 + 1 * 21000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Mytilus edulis |
oligomer | alpha1,alpha2,IC1,IC2,IC3,LC2,LC3,LC4, 1 * 450000 + 1 * 430000 + 1 * 130000 + 1 * 96000 + 1 * 82500 + 1* 19000 + 1 * 16500 + 1 * 14500, dynein polypeptides from flagella, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |
oligomer | alpha1,alpha2,IC2,IC3,LC2,LC3, 1 * 450000 + 1 * 430000 + 1 * 90000 + 1 * 78000 + 1* 20000 + 1 * 17000, dynein polypeptides from cilia, heavy chains, intermediate chains (IC) and light chains (LC), SDS-PAGE | Spisula solidissima |