Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Chlamydomonas reinhardtii | |
ADP | inhibits both ATPase and severing activities | Strongylocentrotus purpuratus | |
ATPgammaS | - |
Chlamydomonas reinhardtii | |
ATPgammaS | - |
Strongylocentrotus purpuratus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Chlamydomonas reinhardtii | 5737 | - |
cytoplasm | - |
Strongylocentrotus purpuratus | 5737 | - |
cytoplasm | - |
Actinocoryne sp. | 5737 | - |
endoplasmic reticulum | - |
Chlamydomonas reinhardtii | 5783 | - |
endoplasmic reticulum | - |
Strongylocentrotus purpuratus | 5783 | - |
endoplasmic reticulum | - |
Actinocoryne sp. | 5783 | - |
Golgi apparatus | - |
Chlamydomonas reinhardtii | 5794 | - |
Golgi apparatus | - |
Strongylocentrotus purpuratus | 5794 | - |
Golgi apparatus | - |
Actinocoryne sp. | 5794 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
gel filtration | Strongylocentrotus purpuratus |
81000 | - |
gel filtration | Strongylocentrotus purpuratus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Chlamydomonas reinhardtii | - |
ADP + phosphate | - |
? | |
ATP + H2O | Xenopus laevis | - |
ADP + phosphate | - |
? | |
ATP + H2O | Spisula solidissima | - |
ADP + phosphate | - |
? | |
ATP + H2O | Strongylocentrotus purpuratus | - |
ADP + phosphate | - |
? | |
ATP + H2O | Actinocoryne sp. | - |
ADP + phosphate | - |
? | |
GTP + H2O | Chlamydomonas reinhardtii | - |
GDP + phosphate | - |
? | |
GTP + H2O | Xenopus laevis | - |
GDP + phosphate | - |
? | |
GTP + H2O | Spisula solidissima | - |
GDP + phosphate | - |
? | |
GTP + H2O | Strongylocentrotus purpuratus | - |
GDP + phosphate | - |
? | |
GTP + H2O | Actinocoryne sp. | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Actinocoryne sp. | - |
- |
- |
Chlamydomonas reinhardtii | - |
- |
- |
Spisula solidissima | - |
- |
- |
Strongylocentrotus purpuratus | - |
sea urchin | - |
Xenopus laevis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
copurification of p81 and p60 | Strongylocentrotus purpuratus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Chlamydomonas reinhardtii | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Xenopus laevis | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Spisula solidissima | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Strongylocentrotus purpuratus | |
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Actinocoryne sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Chlamydomonas reinhardtii | ADP + phosphate | - |
? | |
ATP + H2O | - |
Xenopus laevis | ADP + phosphate | - |
? | |
ATP + H2O | - |
Spisula solidissima | ADP + phosphate | - |
? | |
ATP + H2O | - |
Strongylocentrotus purpuratus | ADP + phosphate | - |
? | |
ATP + H2O | - |
Actinocoryne sp. | ADP + phosphate | - |
? | |
GTP + H2O | - |
Chlamydomonas reinhardtii | GDP + phosphate | - |
? | |
GTP + H2O | - |
Xenopus laevis | GDP + phosphate | - |
? | |
GTP + H2O | - |
Spisula solidissima | GDP + phosphate | - |
? | |
GTP + H2O | - |
Strongylocentrotus purpuratus | GDP + phosphate | - |
? | |
GTP + H2O | - |
Actinocoryne sp. | GDP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Chlamydomonas reinhardtii |
dimer | - |
Xenopus laevis |
dimer | - |
Actinocoryne sp. |
dimer | 1 * 81000 + 1 * 60000, SDS-PAGE | Strongylocentrotus purpuratus |
Synonyms | Comment | Organism |
---|---|---|
microtubule-stimulated ATPase | - |
Strongylocentrotus purpuratus |
p81-p60 | - |
Strongylocentrotus purpuratus |