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Literature summary for 5.5.1.4 extracted from
- Purification and characterisation of myo-inositol-1-phosphate synthase of the yeast Candida utilis (1994), Biokemistri, 4, 97-102.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | reactivation by some divalent cations | Cyberlindnera jadinii |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.06 | - |
glucose 6-phosphate | - |
Cyberlindnera jadinii | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | slight activation | Cyberlindnera jadinii | |
| Mn2+ | activation | Cyberlindnera jadinii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 105000 | - |
gel filtration | Cyberlindnera jadinii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Glucose 6-phosphate | Cyberlindnera jadinii | key enzyme in myo-inositol biosynthetic pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cyberlindnera jadinii | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Cyberlindnera jadinii |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Cyberlindnera jadinii |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, very stable in 0.1 M Tris-acetate buffer, pH 7.8, 14% loss of activity after 7 days and 51% loss of activity after 1 month | Cyberlindnera jadinii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Glucose 6-phosphate | - |
Cyberlindnera jadinii | L-myo-Inositol 1-phosphate | - |
? | |
| D-Glucose 6-phosphate | key enzyme in myo-inositol biosynthetic pathway | Cyberlindnera jadinii | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
- |
Cyberlindnera jadinii |
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