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Information on EC 5.5.1.4 - inositol-3-phosphate synthase

for references in articles please use BRENDA:EC5.5.1.4
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IUBMB Comments
Requires NAD+, which dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form.
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The expected taxonomic range for this enzyme is: Eukaryota, Archaea, Bacteria
Synonyms
1D-myo-inositol 3-phosphate synthase, 1L-myo-Inositol-1-phosphate synthase, AtMIPS1, AtMIPS2-1, AtMIPS3, CaMIPS1, CaMIPS2, D-Glucose 6-phosphate cycloaldolase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cyclase, D-Glucose 6-phosphate-1L-myoinositol 1-phosphate cycloaldolase, more
REACTION
REACTION DIAGRAM
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UNIPROT
LITERATURE
D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
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D-glucose 6-phosphate = L-myo-inositol 1-phosphate
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