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Literature summary for 5.4.99.9 extracted from

  • Eppe, G.; Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrieres, V.; Vincent, S.P.
    Probing UDP-galactopyranose mutase binding pocket: A dramatic effect on substitution of the 6-position of UDP-galactofuranose (2008), Bioorg. Med. Chem. Lett., 19, 814-816.
    View publication on PubMed
Search for more literature for 5.4.99.9

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.022
-
 UDP-galactofuranose
-
 Mycobacterium tuberculosis
0.022
-
 UDP-galactopyranose
-
 Escherichia coli
0.065
-
 UDP-2-deoxy-2-fluoro-D-galactofuranose
-
 Escherichia coli
0.065
-
 UDP-2-fluoro-galactofuranose
-
 Mycobacterium tuberculosis
0.6
-
 UDP-L-arabinofuranose
-
 Escherichia coli
0.861
-
 UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Escherichia coli
0.861
-
 UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Mycobacterium tuberculosis
24
-
 UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Escherichia coli
24
-
 UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Mycobacterium tuberculosis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Escherichia coli UDP-(6-deoxy-6-fluoro)-D-galactopyranose
-
 r
UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Mycobacterium tuberculosis ?
-
 ?
UDP-2-deoxy-2-fluoro-D-galactofuranose
-
 Escherichia coli ?
-
 ?
UDP-2-fluoro-galactofuranose
-
 Mycobacterium tuberculosis ?
-
 ?
UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Escherichia coli ?
-
 ?
UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Mycobacterium tuberculosis ?
-
 ?
UDP-beta-L-arabinofuranose
-
 Mycobacterium tuberculosis ?
-
 ?
UDP-galactopyranose
-
 Escherichia coli UDP-galactofuranose
-
 r
UDP-galactopyranose
-
 Mycobacterium tuberculosis UDP-galactofuranose
-
 r
UDP-L-arabinofuranose
-
 Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
UGM
-
 Escherichia coli
UGM
-
 Mycobacterium tuberculosis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.033
-
 UDP-2-deoxy-2-fluoro-D-galactofuranose
-
 Escherichia coli
0.033
-
 UDP-2-fluoro-galactofuranose
-
 Mycobacterium tuberculosis
5.7
-
 UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Escherichia coli
5.7
-
 UDP-3-deoxy-3-fluoro-D-galactofuranose
-
 Mycobacterium tuberculosis
7.4
-
 UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Escherichia coli
7.4
-
 UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Mycobacterium tuberculosis
12
-
 UDP-L-arabinofuranose
-
 Escherichia coli
27
-
 UDP-galactofuranose
-
 Mycobacterium tuberculosis
27
-
 UDP-galactopyranose
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Escherichia coli
FAD
-
 Mycobacterium tuberculosis

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.34
-
 UDP-(6-deoxy-6-fluoro)-D-galactofuranose
-
 Mycobacterium tuberculosis
0.41
-
 UDP-2-fluoro-galactofuranose
-
 Mycobacterium tuberculosis
1230
-
 UDP-galactofuranose
-
 Mycobacterium tuberculosis