Application | Comment | Organism |
---|---|---|
medicine | MPGES-1 is an alternative therapeutic target in cancer cells expressing this enzyme | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | Homo sapiens | - |
Prostaglandin E2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
DU-145 cell | - |
Homo sapiens | - |
additional information | MPGES-1 is not detected in LNCaP cells | Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Homo sapiens | Prostaglandin E2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
microsomal prostaglandin E synthase 1 | - |
Homo sapiens |
mPGES-1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | interleukin-1beta does not change expression of MPGES-1 in the prostate cancer cell lines | additional information |