Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | 0.1 mM, causes 4fold increase in activity | Chironomus sp. |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Chironomus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Mn2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Pb2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Zn2+ | 0.1 mM, inhibits over 90% of the enzyme activity | Chironomus sp. |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | 0.1 mM, causes 4fold increase in activity | Chironomus sp. | |
Fe2+ | present in the cluster of the recombinant enzyme complex | Chironomus sp. | |
Mg2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Mn2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Pb2+ | 0.1 mM, reduces the enzymatic activity by more than 60% | Chironomus sp. | |
Zn2+ | 0.1 mM, inhibits over 90% of the enzyme activity | Chironomus sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41200 | - |
monomer, calculated from amino acid sequence | Chironomus sp. |
43000 | - |
x * 43000, SDS-PAGE | Chironomus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin + Fe2+ | Chironomus sp. | - |
protoheme + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chironomus sp. | Q967G9 | chironomid larvae | - |
Purification (Comment) | Organism |
---|---|
- |
Chironomus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin + Fe2+ | - |
Chironomus sp. | protoheme + H+ | - |
? | |
protoporphyrin IX + Fe2+ | pH 8.0, 37°C | Chironomus sp. | protoheme + 2 H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000, SDS-PAGE | Chironomus sp. |
Synonyms | Comment | Organism |
---|---|---|
ferrochelatase | - |
Chironomus sp. |