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Literature summary for 4.6.1.21 extracted from
- Residue specificity of a ribonuclease which hydrolyzes polycytidylic acid (1970), J. Biol. Chem., 245, 3257-3262.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | - |
Enterobacter sp. |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | inhibition after enzyme dialysis against 0.001 M EDTA | Enterobacter sp. |  |
| o-phenanthroline | inhibition after enzyme dialysis against 0.001 M o-phenanthroline | Enterobacter sp. | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Cd2+ | reverses EDTA- and o-phenanthroline-induced inhibition | Enterobacter sp. | |
| Co2+ | reverses EDTA- and o-phenanthroline-induced inhibition | Enterobacter sp. | |
| Mg2+ | reverses EDTA- and o-phenanthroline-induced inhibition | Enterobacter sp. | |
| Mn2+ | reverses EDTA- and o-phenanthroline-induced inhibition | Enterobacter sp. | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA + H2O | Enterobacter sp. | preferential cleavage at CpA | nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Enterobacter sp. | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Enterobacter sp. |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -15°C, stable, withstands freezing and thawing | Enterobacter sp. |
| -196°C, stable, withstands freezing and thawing | Enterobacter sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA + H2O | preferential cleavage at CpA | Enterobacter sp. | nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | - |
Enterobacter sp. |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | - |
no activity below, poly(C) | Enterobacter sp. |
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Release 2023.1 (January 2023)
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