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Literature summary for 4.6.1.19 extracted from

  • Hillwig, M.S.; Contento, A.L.; Meyer, A.; Ebany, D.; Bassham, D.C.; Macintosh, G.C.
    RNS2, a conserved member of the RNase T2 family, is necessary for ribosomal RNA decay in plants (2011), Proc. Natl. Acad. Sci. USA, 108, 1093-1098.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.19

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum and derived structures, e.g. endoplasmic reticulum-derived bodies Arabidopsis thaliana 5783
-
vacuole
-
 Arabidopsis thaliana 5773
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana RNS2 is not an acidic RNase ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 gene rns2
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Source Tissue

Source Tissue Comment Organism Textmining
additional information the enzyme is the main endoribonuclease activity in plant cells Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information RNS2 is not an acidic RNase Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
More the enzyme is a conserved member of the RNase T2 family Arabidopsis thaliana
RNase T2
-
 Arabidopsis thaliana
RNS2
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
evolution RNS2 is part of a process that degrades rRNA to recycle its components and is conserved in all eukaryotes Arabidopsis thaliana
malfunction mutants lacking RNS2 activity accumulate RNA intracellularly, and rRNA in these mutants has a longer half-life, rns2 mutants display constitutive autophagy, phenotypes, overview Arabidopsis thaliana
physiological function RNS2, an intracellular RNase T2 from Arabidopsis thaliana, is essential for normal ribosomal RNA recycling. RNS2 is part of a process that degrades rRNA to recycle its components Arabidopsis thaliana