Literature summary for 4.4.1.11 extracted from

Huang, K.Y.; Hu, H.Y.; Tang, Y.L.; Xia, F.G.; Luo, X.Q.; Liu, J.Z.
High-level expression, purification and large-scale production of L-methionine gamma-lyase from Idiomarina as a novel anti-leukemic drug (2015), Mar. Drugs, 13, 5492-5507 .

Search for more literature for 4.4.1.11

Application

Application	Comment	Organism
medicine	the enzyme significantly inhibits proliferation of leukemia cell lines and induces cellular apoptosis	Idiomarina sp.

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Idiomarina sp.

Organism

Organism	UniProt	Comment	Textmining
Idiomarina sp.	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant protein	Idiomarina sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
108	-	pH not specified in the publication, temperature not specified in the publication	Idiomarina sp.

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-methionine + H2O	-	Idiomarina sp.	methanethiol + NH3 + 2-oxobutanoate	-	?

Subunits

Subunits	Comment	Organism
?	x * 46000, SDS-PAGE	Idiomarina sp.

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Release 2023.1 (January 2023)