Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.3.1.2 extracted from

  • Akhtar, M.; Cohen, M.A.; Gani, D.
    Enzymic synthesis of 3-halogenoaspartic acids using beta-methylaspartase: Inhibition by 3-bromoaspartic acid (1980), J. Chem. Soc. Chem. Commun., 1986, 1290-1291.
No PubMed abstract available
Search for more literature for 4.3.1.2

Application

Application Comment Organism
synthesis enzyme is used for L-aspartic acid production Clostridium tetanomorphum

Inhibitors

Inhibitors Comment Organism Structure
3-bromoaspartate irreversible Clostridium tetanomorphum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-threo-3-methylaspartate Clostridium tetanomorphum
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium tetanomorphum
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-threo-3-methylaspartate = mesaconate + NH3 mechanism Clostridium tetanomorphum
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-bromoaspartate
-
 Clostridium tetanomorphum bromofumarate + NH3 during reaction, enzyme becomes inactive. This is reduced in the presence of alternative substrates ?
3-chloroaspartate
-
 Clostridium tetanomorphum chlorofumarate + NH3
-
 ?
L-aspartate (2S)-aspartate Clostridium tetanomorphum fumarate + NH3
-
 ?
L-threo-3-methylaspartate r Clostridium tetanomorphum mesaconate + NH3
-
 ?
L-threo-3-methylaspartate (2S,3S)-3-methylaspartic acid Clostridium tetanomorphum mesaconate + NH3
-
 ?
L-threo-3-methylaspartate
-
 Clostridium tetanomorphum ?
-
 ?