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Literature summary for 4.2.1.9 extracted from

  • Armstrong, F.B.; Lipscomb, E.L.; Crout, D.H.G.; Morgan, P.J.
    Structure-activity studies with alpha,beta-dihydroxyacid dehydratase of Salmonella typhimurium (1985), J. Chem. Soc. Perkin Trans., 1, 691-696.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-dihydroxy-3-methylpentanoate Salmonella enterica subsp. enterica serovar Typhimurium 2R,3R-(2,3)-dihydroxy-3-methylpentanoate ?
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?

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-2,3-dihydroxy-3-ethylpentanoate 20% of the activity with 2,3-dihydroxyisovalerate Salmonella enterica subsp. enterica serovar Typhimurium ?
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?
2,3-dihydroxy-3-methylbutanoate
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Salmonella enterica subsp. enterica serovar Typhimurium 2-oxoisovalerate + H2O
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?
2,3-dihydroxy-3-methylpentanoate 2R,3R-(2,3)-dihydroxy-3-methylpentanoate, at 45% of the activity with 2,3-dihydroxyisovalerate Salmonella enterica subsp. enterica serovar Typhimurium 3-methyl-2-oxopentanoate + H2O
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?
2,3-dihydroxy-3-methylpentanoate 2R,3R-(2,3)-dihydroxy-3-methylpentanoate Salmonella enterica subsp. enterica serovar Typhimurium ?
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?
threo-2,3-dihydroxybutanoate at 45% of the activity with 2,3-dihydroxyisovalerate Salmonella enterica subsp. enterica serovar Typhimurium ?
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?