Activating Compound | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | allosteric activator, in the presence of AdoMet, the autoinhibition exerted by the regulatory region is eliminated | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
structure of CBS with bound AdoMet. Binding of AdoMet triggers a conformational change in the Bateman module of the regulatory domain that favors its association with a Bateman module of the complementary subunit to form an antiparallel CBS module. In the presence of AdoMet, the autoinhibition exerted by the regulatory region is eliminated | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P35520 | - |
- |