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Literature summary for 4.2.1.22 extracted from

  • Saha, S.; Chakraborty, P.K.; Xiong, X.; Dwivedi, S.K.; Mustafi, S.B.; Leigh, N.R.; Ramchandran, R.; Mukherjee, P.; Bhattacharya, R.
    Cystathionine beta-synthase regulates endothelial function via protein S-sulfhydration (2016), FASEB J., 30, 441-456 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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General Information

General Information Comment Organism
physiological function the loss of CBS function in endothelial cells leads to a significant down-regulation of cellular hydrogen sulfide by 50% and of glutathione by 40%. Silencing CBS in endothelial cells compromises phenotypic and signaling responses to the vascular endothelial growth factor Homo sapiens