Literature summary for 4.2.1.167 extracted from

Bendrat, K.; Mueller, U.; Klees, A.G.; Buckel, W.
Identification of the gene encoding the activator of (R)-2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans by gene expression in Escherichia coli (1993), FEBS Lett., 329, 329-331.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	enzyme requires an activator protein HgdC for activity. Dehydratase activity is stimulated at least tenfold by cell-free extracts of Escherichia coli cells transformed with a plasmid carrying hgdC. On the chromosome the HgdC gene is located just before the catalytic subunits hgdA and hgdB	Acidaminococcus fermentans

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Acidaminococcus fermentans

Organism

Organism	UniProt	Comment	Textmining
Acidaminococcus fermentans	P11569 and P11570 and P11568	P11569 i.e. subunit alpha, P11570 i.e. subunit beta, P11568 i.e. activator protein	-
Acidaminococcus fermentans DSM 20731	P11569 and P11570 and P11568	P11569 i.e. subunit alpha, P11570 i.e. subunit beta, P11568 i.e. activator protein	-

Synonyms

Synonyms	Comment	Organism
HgdC	activator protein	Acidaminococcus fermentans

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Release 2023.1 (January 2023)