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Literature summary for 4.2.1.123 extracted from
- Lateral transfer of tetrahymanol-synthesizing genes has allowed multiple diverse eukaryote lineages to independently adapt to environments without oxygen (2012), Biol. Direct, 7, 0000.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| phylogenetic analysis | Tetrahymena pyriformis |
| phylogenetic analysis | Paramecium tetraurelia |
| phylogenetic analysis | Piromyces sp. |
| phylogenetic analysis | Alvinella pompejana |
| phylogenetic analysis | Paratrimastix pyriformis |
| phylogenetic analysis | Stygiella incarcerata |
| phylogenetic analysis | Sawyeria marylandensis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| squalene + H2O | Tetrahymena pyriformis | - |
tetrahymanol | - |
? |  |
| squalene + H2O | Paramecium tetraurelia | - |
tetrahymanol | - |
? | |
| squalene + H2O | Piromyces sp. | - |
tetrahymanol | - |
? | |
| squalene + H2O | Alvinella pompejana | - |
tetrahymanol | - |
? | |
| squalene + H2O | Paratrimastix pyriformis | - |
tetrahymanol | - |
? | |
| squalene + H2O | Stygiella incarcerata | - |
tetrahymanol | - |
? | |
| squalene + H2O | Sawyeria marylandensis | - |
tetrahymanol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Alvinella pompejana | - |
- |
- |
| Paramecium tetraurelia | - |
- |
- |
| Paratrimastix pyriformis | - |
- |
- |
| Piromyces sp. | - |
- |
- |
| Sawyeria marylandensis | - |
- |
- |
| Stygiella incarcerata | - |
- |
- |
| Tetrahymena pyriformis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| squalene + H2O | - |
Tetrahymena pyriformis | tetrahymanol | - |
? | |
| squalene + H2O | - |
Paramecium tetraurelia | tetrahymanol | - |
? | |
| squalene + H2O | - |
Piromyces sp. | tetrahymanol | - |
? | |
| squalene + H2O | - |
Alvinella pompejana | tetrahymanol | - |
? | |
| squalene + H2O | - |
Paratrimastix pyriformis | tetrahymanol | - |
? | |
| squalene + H2O | - |
Stygiella incarcerata | tetrahymanol | - |
? | |
| squalene + H2O | - |
Sawyeria marylandensis | tetrahymanol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| squalene-tetrahymanol cyclase | - |
Tetrahymena pyriformis |
| squalene-tetrahymanol cyclase | - |
Paramecium tetraurelia |
| squalene-tetrahymanol cyclase | - |
Piromyces sp. |
| squalene-tetrahymanol cyclase | - |
Alvinella pompejana |
| squalene-tetrahymanol cyclase | - |
Paratrimastix pyriformis |
| squalene-tetrahymanol cyclase | - |
Stygiella incarcerata |
| squalene-tetrahymanol cyclase | - |
Sawyeria marylandensis |
| STC | - |
Tetrahymena pyriformis |
| STC | - |
Paramecium tetraurelia |
| STC | - |
Piromyces sp. |
| STC | - |
Alvinella pompejana |
| STC | - |
Paratrimastix pyriformis |
| STC | - |
Stygiella incarcerata |
| STC | - |
Sawyeria marylandensis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Tetrahymena pyriformis |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Paramecium tetraurelia |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Piromyces sp. |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Alvinella pompejana |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Paratrimastix pyriformis |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Stygiella incarcerata |
| evolution | genes encoding the tetrahymanol synthesizing enzyme squalene-tetrahymanol cyclase are found from several phylogenetically diverged eukaryotes that live in oxygen-poor environments and appear to have been laterally transferred among such eukaryotes, overview | Sawyeria marylandensis |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Tetrahymena pyriformis |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Paramecium tetraurelia |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Piromyces sp. |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Alvinella pompejana |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Paratrimastix pyriformis |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Stygiella incarcerata |
| additional information | tetrahymanol, a triterpenoid that does not require molecular oxygen for its biosynthesis, likely functions as a surrogate of sterol in eukaryotes inhabiting oxygen-poor environments | Sawyeria marylandensis |
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