Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene | - |
Methanosarcina thermophila | |
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene | - |
Methanothermobacter thermautotrophicus | |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine | - |
Methanosarcina thermophila | |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine | - |
Methanothermobacter thermautotrophicus | |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine | - |
Methanosarcina thermophila | |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine | - |
Methanothermobacter thermautotrophicus | |
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline | - |
Methanosarcina thermophila | |
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline | - |
Methanothermobacter thermautotrophicus | |
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline | - |
Methanosarcina thermophila | |
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline | - |
Methanothermobacter thermautotrophicus | |
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline | - |
Methanosarcina thermophila | |
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline | - |
Methanothermobacter thermautotrophicus | |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide | - |
Methanosarcina thermophila | |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide | - |
Methanothermobacter thermautotrophicus | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline | - |
Methanosarcina thermophila | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline | - |
Methanothermobacter thermautotrophicus | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline | - |
Methanosarcina thermophila | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline | - |
Methanothermobacter thermautotrophicus | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline | - |
Methanosarcina thermophila | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline | - |
Methanothermobacter thermautotrophicus | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline | - |
Methanosarcina thermophila | |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline | - |
Methanothermobacter thermautotrophicus | |
acetazolamide | - |
Methanosarcina thermophila | |
acetazolamide | - |
Methanothermobacter thermautotrophicus | |
celecoxib | - |
Methanosarcina thermophila | |
celecoxib | - |
Methanothermobacter thermautotrophicus | |
dorzolamide | - |
Methanosarcina thermophila | |
dorzolamide | - |
Methanothermobacter thermautotrophicus | |
ethoxzolamide | - |
Methanosarcina thermophila | |
ethoxzolamide | - |
Methanothermobacter thermautotrophicus | |
methazolamide | - |
Methanosarcina thermophila | |
methazolamide | - |
Methanothermobacter thermautotrophicus | |
sulfamic acid | - |
Methanosarcina thermophila | |
sulfamic acid | - |
Methanothermobacter thermautotrophicus | |
sulfamide | - |
Methanosarcina thermophila | |
sulfamide | - |
Methanothermobacter thermautotrophicus | |
sulfanilamide | - |
Methanosarcina thermophila | |
sulfanilamide | - |
Methanothermobacter thermautotrophicus | |
topiramate | - |
Methanosarcina thermophila | |
topiramate | - |
Methanothermobacter thermautotrophicus | |
valdecoxib | - |
Methanosarcina thermophila | |
valdecoxib | - |
Methanothermobacter thermautotrophicus | |
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine | - |
Methanosarcina thermophila | |
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine | - |
Methanothermobacter thermautotrophicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanosarcina thermophila | P40881 | - |
- |
Methanothermobacter thermautotrophicus | - |
- |
- |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
assay at | Methanothermobacter thermautotrophicus |
20 | - |
assay at | Methanosarcina thermophila |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000063 | - |
acetazolamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.000096 | - |
sulfamic acid | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00012 | - |
topiramate | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00012 | - |
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00013 | - |
valdecoxib | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00014 | - |
methazolamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00014 | - |
celecoxib | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00014 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00015 | - |
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00017 | - |
methazolamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00017 | - |
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00018 | - |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00019 | - |
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.0002 | - |
ethoxzolamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00022 | - |
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00024 | - |
valdecoxib | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00025 | - |
sulfanilamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00027 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00028 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00028 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00035 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00041 | - |
dorzolamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00061 | - |
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00066 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00074 | - |
ethoxzolamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00074 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00083 | - |
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00095 | - |
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00097 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00101 | - |
celecoxib | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00102 | - |
topiramate | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00124 | - |
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.0013 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00143 | - |
acetazolamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00171 | - |
dorzolamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00172 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.0022 | - |
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.00336 | - |
sulfamic acid | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00393 | - |
sulfanilamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.0042 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00535 | - |
ethoxzolamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.00596 | - |
sulfamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.00636 | - |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.0085 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine | 20°C, pH not specified in the publication, Co2+-containing enzyme | Methanosarcina thermophila | |
0.012 | - |
acetazolamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0143 | - |
3-[amino(dihydroxy)-lambda4-sulfanyl]aniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0235 | - |
topiramate | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0257 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]ethanamine | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0285 | - |
1-[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]methanamine | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0307 | - |
dorzolamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.032 | - |
methazolamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0385 | - |
celecoxib | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.05 | - |
2,4-bis[amino(dihydroxy)-lamba4-sulfanyl]-5-(trifluoromethyl)aniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0524 | - |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0534 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-fluoroaniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0578 | - |
sulfanilamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.061 | - |
valdecoxib | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.0621 | - |
2,4-bis[amino(dihydroxy)-lambda4-sulfanyl]-5-chloroaniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.069 | - |
sulfamide | 20°C, pH not specified in the publication, Zn2+-containing enzyme | Methanosarcina thermophila | |
0.077 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-bromoaniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.098 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-iodoaniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.105 | - |
1,5-bis[amino(dihydroxy)-lambda4-sulfanyl]-2,3-dichlorobenzene | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.111 | - |
4-[amino(dihydroxy)-lambda4-sulfanyl]-2-chloroaniline | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
0.127 | - |
[4-[amino(dihydroxy)-lambda4-sulfanyl]phenyl]hydrazine | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
44 | - |
sulfamide | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus | |
103 | - |
sulfamic acid | 20°C, pH not specified in the publication | Methanothermobacter thermautotrophicus |