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Literature summary for 4.1.2.29 extracted from
- The pathway of myo-inositol degradation in Aerobacter aerogenes. Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates (1971), J. Biol. Chem., 246, 5662-5675.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no requirement | Klebsiella aerogenes |
General Stability
| General Stability | Organism |
|---|---|
| resistant to repeated freezing and thawing | Klebsiella aerogenes |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NaBH4 | - |
Klebsiella aerogenes |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.037 | - |
6-phospho-5-dehydro-2-deoxy-D-gluconate | - |
Klebsiella aerogenes | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-Phospho-5-dehydro-2-deoxy-D-gluconate | Klebsiella aerogenes | enzyme is involved in myo-inositol catabolism | ? | - |
? | |
| 6-Phospho-5-dehydro-2-deoxy-D-gluconate | Klebsiella aerogenes constitutive | enzyme is involved in myo-inositol catabolism | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Klebsiella aerogenes | - |
- |
- |
Oxidation Stability
| Oxidation Stability | Organism |
|---|---|
| inactivation by reduction with NaBH4 in presence of dihydroxyaceton phosphate | Klebsiella aerogenes |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Klebsiella aerogenes |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-phospho-5-dehydro-2-deoxy-D-gluconate | - |
Klebsiella aerogenes | glycerone phosphate + malonate semialdehyde | - |
? | |
| 6-phospho-5-dehydro-2-deoxy-D-gluconate | - |
Klebsiella aerogenes constitutive | glycerone phosphate + malonate semialdehyde | - |
? | |
| 6-Phospho-5-dehydro-2-deoxy-D-gluconate | enzyme is involved in myo-inositol catabolism | Klebsiella aerogenes | ? | - |
? | |
| 6-Phospho-5-dehydro-2-deoxy-D-gluconate | enzyme is involved in myo-inositol catabolism | Klebsiella aerogenes constitutive | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8.7 | - |
Klebsiella aerogenes |
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Release 2023.1 (January 2023)
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