Information on EC 4.1.2.29 - 5-dehydro-2-deoxyphosphogluconate aldolase

for references in articles please use BRENDA:EC4.1.2.29
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The expected taxonomic range for this enzyme is: Klebsiella aerogenes

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EC NUMBER
COMMENTARY hide
4.1.2.29
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RECOMMENDED NAME
GeneOntology No.
5-dehydro-2-deoxyphosphogluconate aldolase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-dehydro-2-deoxy-D-gluconate 6-phosphate = glycerone phosphate + malonate semialdehyde
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
elimination
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of an aldehyde, C-C bond cleavage
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
myo-inositol degradation I
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myo-inositol biosynthesis
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Inositol phosphate metabolism
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Metabolic pathways
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Microbial metabolism in diverse environments
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SYSTEMATIC NAME
IUBMB Comments
5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming)
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CAS REGISTRY NUMBER
COMMENTARY hide
62213-25-6
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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-
-
Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6-Phospho-5-dehydro-2-deoxy-D-gluconate
?
show the reaction diagram
6-Phospho-5-dehydro-2-deoxy-D-gluconate
Glycerone phosphate + malonate semialdehyde
show the reaction diagram
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-Phospho-5-dehydro-2-deoxy-D-gluconate
?
show the reaction diagram
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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
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no requirement
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.037
6-phospho-5-dehydro-2-deoxy-D-gluconate
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-
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
resistant to repeated freezing and thawing
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OXIDATION STABILITY
ORGANISM
UNIPROT
LITERATURE
inactivation by reduction with NaBH4 in presence of dihydroxyaceton phosphate
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5124
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
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Show AA Sequence (124 entries)
Please use the Sequence Search for a specific query.
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LINKS TO OTHER DATABASES (specific for EC-Number 4.1.2.29)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)