Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.6.1.9 extracted from

  • Belli, S.I.; Goding, J.W.
    Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities (1994), Eur. J. Biochem., 226, 433-443.
    View publication on PubMed
Search for more literature for 3.6.1.9

Cloned(Commentary)

Cloned (Comment) Organism
expression in Cos-7 and mouse Ltk- cells Homo sapiens
expression in Cos-7 and mouse Ltk- cells Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
120000
-
 2 * 120000, reducing SDS-PAGE Mus musculus
130000
-
 2 * 130000, reducing SDS-PAGE, disulfide-bound Homo sapiens
240000
-
 non-reducing SDS-PAGE Mus musculus
260000
-
 non-reducing SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Homo sapiens
-
 AMP + phosphate
-
 ?
ATP + H2O Mus musculus
-
 AMP + diphosphate
-
 ?
ATP + H2O Homo sapiens
-
 AMP + diphosphate
-
 ?
UDP-glucose + H2O Homo sapiens
-
 UMP + D-glucose-1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein N-linked oligosaccharides, human 120 kDa-precursor form possesses high-mannose oligosaccharides, which disappear in the mature 130 kDa form Homo sapiens
glycoprotein N-linked oligosaccharides, human 120 kDa-precursor form possesses high-mannose oligosaccharides, which disappear in the mature 130 kDa form Mus musculus
phosphoprotein autophosphorylation Homo sapiens
phosphoprotein autophosphorylation Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Homo sapiens AMP + phosphate
-
 ?
ATP + H2O
-
 Mus musculus AMP + diphosphate
-
 ?
ATP + H2O
-
 Homo sapiens AMP + diphosphate
-
 ?
p-nitrophenyl phenylphosphonate + H2O phosphodiesterase-1 activity Mus musculus p-nitrophenol + phenylphosphonate
-
 ?
p-nitrophenyl phenylphosphonate + H2O phosphodiesterase-1 activity Homo sapiens p-nitrophenol + phenylphosphonate
-
 ?
UDP-glucose + H2O
-
 Homo sapiens UMP + D-glucose-1-phosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 130000, reducing SDS-PAGE, disulfide-bound Homo sapiens
dimer 2 * 120000, reducing SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
nucleotide pyrophosphatase/phosphodiesterase-I
-
 Homo sapiens
nucleotide pyrophosphatase/phosphodiesterase-I
-
 Mus musculus