Literature summary for 3.6.1.5 extracted from

Magalhaes, L.; de Oliveira, A.H.C.; de Souza Vasconcellos, R.; Mariotini-Moura, C.; de Cassia Firmino, R.; Fietto, J.L.R.; Cardoso, C.L.
Label-free assay based on immobilized capillary enzyme reactor of Leishmania infantum nucleoside triphosphate diphosphohydrolase (LicNTPDase-2-ICER-LC/UV) (2016), J. Chromatogr. B, 1008, 98-107 .

Search for more literature for 3.6.1.5

Cloned(Commentary)

Cloned (Comment)	Organism
recombinant expression of LicNTPDase-2	Leishmania infantum

Protein Variants

Protein Variants	Comment	Organism
additional information	purified recombinant LicNTPDase-2 is covalently immobilized onto a fused silica capillary tube to create an immobilized capillary enzyme reactor (ICER) based on LicNTPDase-2(LicNTPDase-2-ICER), development of a label-free online screening method, evaluation of the activity and stability of the enzyme by the multidimensional LicNTPDase-2-ICER method, overview	Leishmania infantum

Inhibitors

Inhibitors	Comment	Organism	Structure
suramin	noncompetitive inhibition, inhibition mechanism analysis, overview	Leishmania infantum

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
additional information	-	additional information	kinetic analysis	Leishmania infantum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ADP + H2O	Leishmania infantum	-	AMP + phosphate	-	?
ATP + 2 H2O	Leishmania infantum	-	AMP + 2 phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Leishmania infantum	K7ZBX8	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant LicNTPDase-2	Leishmania infantum

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ADP + H2O	-	Leishmania infantum	AMP + phosphate	-	?
ATP + 2 H2O	-	Leishmania infantum	AMP + 2 phosphate	-	?

Synonyms

Synonyms	Comment	Organism
LicNTPDase-2	-	Leishmania infantum
nucleoside triphosphate diphosphohydrolase 2	-	Leishmania infantum

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
22	-	assay at room temperature	Leishmania infantum

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8	-	assay at	Leishmania infantum

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Release 2023.1 (January 2023)