Cloned (Comment) | Organism |
---|---|
expression of 3H9 VDJ knock-in alleles in genomic DNA of immature/T1, mature follicular B cells, and thymocytes from 3H9 and 3H9.Aicda-/- mice, quantitative expression analysis by PCR and immunofluorescence | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of several enzyme-deficient Aicda-/- mice | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
gene Aicda | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-lymphocyte | AID expression occurs first in pro-B cells and increases on further development, peak AID expression is in immature and T1 B cells from bone marrow, is lower in splenic T1 B cells, and decreases precipitously in the splenic transitional 2 and mature B-cell compartments | Mus musculus | - |
additional information | AID cDNA is undetectable in totipotent hematopoietic progenitors, and in cells committed to the T lymphocyte or myeloid lineages | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
activation-induced cytidine deaminase | - |
Mus musculus |
AICDA | - |
Mus musculus |