Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ovis aries | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Ovis aries | - |
pulmonary artery endothelium | - |
Ovis aries | - |
Synonyms | Comment | Organism |
---|---|---|
GCH1 | - |
Ovis aries |
Organism | Comment | Expression |
---|---|---|
Ovis aries | exposure to the NO donor spermine NONOate (0-0.1 mM) leads to an dose-dependent increase in GCH1 protein. GCH1 promoter activity is enhanced by spermine NONOate in a CREB-dependent manner | up |
General Information | Comment | Organism |
---|---|---|
metabolism | GTP cyclohydrolase I is the rate-limiting enzyme in generation of tetrahydrobiopterin | Ovis aries |