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Literature summary for 3.5.4.1 extracted from
- Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells (2015), Microb. Biotechnol., 8, 169-176 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | a Salmonella typhimurium strain overexpressing CodA and resistant to 5-fluorouracyl due to deletion of the Upp gene sequence, after infecting tumour cell cultures, shows increased cytotoxic and bystander effects under standard induction conditions. A PurD mutation in the producer strain controls its intracellular proliferation by the presence of adenine and avoids the intrinsic Salmonella cell death induction | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| codA | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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